Predicting Global Fund grant disbursements for procurement of artemisinin-based combination therapies
2008

Forecasting Global Fund Grant Disbursements for Malaria Treatments

Sample size: 130 publication Evidence: high

Author Information

Author(s): Justin M Cohen, Inder Singh, Megan E O'Brien

Primary Institution: Clinton Foundation HIV/AIDS Initiative

Hypothesis

The rate at which a grant is disbursed can be considered an indicator of grant progress.

Conclusion

The predictive regression models successfully forecasted disbursement patterns for Global Fund malaria grants, indicating their utility for demand forecasting of ACT.

Supporting Evidence

  • Quarterly forecasts were correlated highly with actual smoothed disbursement rates (r = 0.987, p < 0.0001).
  • Predicted ACT procurement was correlated strongly with actual procurement supported by Global Fund grants (r = 0.945, p < 0.0001).
  • Disbursement slopes were positively associated with total agreed funding and negatively associated with phase two funding.

Takeaway

This study created a way to predict how much money the Global Fund will give to countries for malaria treatments, helping ensure that there are enough medicines available.

Methodology

Predictive regression models were derived using a repeated split-sample procedure to estimate disbursement rates from the Global Fund.

Potential Biases

The disbursement rate may not accurately reflect ACT procurement if other components of the grant underperform.

Limitations

Further validation using data from other countries in different regions and environments is necessary to confirm generalizability.

Participant Demographics

The study involved grants from 75 countries or multi-country cooperatives.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1475-2875-7-200

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