Neural Correlates of Perceiving Emotional Faces and Bodies in Developmental Prosopagnosia: An Event-Related fMRI-Study
2008

Neural Correlates of Perceiving Emotional Faces and Bodies in Developmental Prosopagnosia

Sample size: 3 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jan Van den Stock, Wim A. C. van de Riet, Ruthger Righart, Beatrice de Gelder

Primary Institution: Laboratory of Cognitive and Affective Neuroscience, Tilburg University

Hypothesis

How are the neural underpinnings of face and body processing in prosopagnosia influenced by emotional information?

Conclusion

The study shows that developmental prosopagnosics have lower activation for neutral faces but similar activation for emotional faces compared to controls.

Supporting Evidence

  • Emotional information has a different effect in the patient vs. control group in the fusiform face area.
  • Neutral faces trigger lower activation in the developmental prosopagnosics group compared to controls.
  • Developmental prosopagnosics show increased activation for bodies in the inferior occipital gyrus.

Takeaway

Some people have trouble recognizing faces, and this study looked at how their brains react to faces and bodies with different emotions. It found that they struggle more with neutral faces than with emotional ones.

Methodology

Event-related fMRI was used to investigate brain activation in developmental prosopagnosics and matched controls while viewing emotional and neutral faces and bodies.

Potential Biases

Potential selection bias in recruiting participants who self-identified as having prosopagnosia.

Limitations

The study had a small sample size and focused only on three developmental prosopagnosics.

Participant Demographics

Three developmental prosopagnosics (1 female, 2 males) aged 43 to 54, matched with four healthy controls.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0003195

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