Perioperative immunonutrition intervention on postoperative outcomes among gynecological cancer patients under enhanced recovery after surgery setting: A study protocol of explanatory mixed method study
2024

Perioperative Immunonutrition in Gynecological Cancer Patients

Sample size: 106 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ho ChiouYi, Daud Zulfitri Azuan Mat, Mohd Yusof Barakatun Nisak, Abdul Majid Hazreen

Primary Institution: Institut Kanser Negara, Ministry of Health Malaysia

Hypothesis

The study aims to investigate the efficacy and explore patients’ acceptance of the immunonutrition intervention in postoperative outcomes among gynecological cancer patients under the Enhanced Recovery After Surgery framework.

Conclusion

Implementing perioperative immunonutrition intervention within the ERAS framework may contribute to better nutrition status and improved surgical outcomes.

Supporting Evidence

  • Enhanced Recovery After Surgery (ERAS) has shown significant improvements in postoperative outcomes.
  • Immunonutrition (IMN) has been shown to modulate the immune system and inflammatory response.
  • Patients’ perceptions play a pivotal role in enhancing understanding of disease management.

Takeaway

This study is about helping women with cancer recover better after surgery by giving them special nutrition before and after their operation.

Methodology

This study uses a two-phase explanatory sequential mixed-method design, including an open-labeled randomized control trial and a qualitative study.

Potential Biases

Potential bias due to the open-label design where participants and researchers are aware of the assigned interventions.

Limitations

The study may face challenges in patient compliance and understanding of the intervention.

Participant Demographics

Malaysian adult women scheduled for elective surgery for gynecological cancer.

Statistical Information

P-Value

0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0315568

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