Cytomegalovirus retinitis in a seronegative patient with systemic lupus erythematosus on immunosuppressive therapy
2011

Cytomegalovirus Retinitis in a Patient with Lupus

Sample size: 1 publication Evidence: moderate

Author Information

Author(s): Kelkar Aditya, Kelkar Jai, Kelkar Shreekant, Bhirud Shilpa, Biswas Jyotirmoy

Primary Institution: National Institute of Ophthalmology

Hypothesis

Is cytomegalovirus retinitis a risk for seronegative patients with systemic lupus erythematosus on immunosuppressive therapy?

Conclusion

A combination therapy of intravitreal foscarnet with oral and intravenous ganciclovir is effective for treating clinically resistant CMV retinitis in seronegative patients with SLE.

Supporting Evidence

  • The patient had a history of systemic lupus erythematosus and was on immunosuppressive therapy.
  • After treatment, the patient's vision improved significantly.
  • No recurrences were noted up to 6 months after treatment.

Takeaway

This study talks about a woman with lupus who got a serious eye infection. Doctors used special medicines to help her see better again.

Methodology

The patient was treated with a combination of intravitreal ganciclovir, foscarnet, and systemic ganciclovir after tapering her immunosuppressive therapy.

Participant Demographics

A 31-year-old female with systemic lupus erythematosus.

Digital Object Identifier (DOI)

10.1007/s12348-010-0017-3

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