Gut Microbiota's Role in Obstructive Sleep Apnea and Cognitive Impairment
Author Information
Author(s): Tang Mingxing, Wu Yongliang, Liang Junyi, Yang Shuai, Huang Zuofeng, Hu Jing, Yang Qiong, Liu Fei, Li Shuo
Primary Institution: Shenzhen Nanshan People’s Hospital, Shenzhen, China
Hypothesis
Obstructive sleep apnea (OSA) may alter gut microbiota, leading to inflammation and neurocognitive impairment.
Conclusion
The study suggests that modifying gut microbiota could be a potential therapy for OSA-related cognitive dysfunction.
Supporting Evidence
- OSA is linked to high levels of inflammation and cognitive dysfunction.
- Changes in gut microbiota composition can influence inflammation and brain health.
- Fecal microbiota transplantation from OSA models can induce inflammation in naive mice.
Takeaway
Obstructive sleep apnea can change the bacteria in your gut, which might make it harder for your brain to work well.
Methodology
The review discusses findings from clinical studies and animal models regarding the relationship between OSA, gut microbiota, inflammation, and cognitive function.
Limitations
The review is based on existing studies, which may have varying methodologies and sample sizes.
Digital Object Identifier (DOI)
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