5-Bromo-3-(indan-1-yloxy)pyridin-2-amine
2011
Structure of 5-Bromo-3-(indan-1-yloxy)pyridin-2-amine
publication
Evidence: high
Author Information
Author(s): Cho-Schultz Sujin, Kath John C., Moore Curtis, Rheingold Arnold L., Yanovsky Alex
Primary Institution: Pfizer Global Research and Development
Conclusion
The study confirmed the expected structure of the title compound, which was synthesized through a specific chemical reaction.
Supporting Evidence
- The compound was obtained through a specific chemical reaction.
- All C atoms of the indane fragment, except one, are coplanar.
- The study utilized X-ray crystallography to confirm the structure.
Takeaway
Scientists made a new chemical compound and checked its structure to see if it looked like they thought it would.
Methodology
The compound was synthesized by reacting indan-1-yl methanesulfonate with 2-amino-5-bromopyridin-3-ol in the presence of caesium carbonate, followed by crystallization.
Digital Object Identifier (DOI)
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