Buffered Articaine Reduces Pain and Improves Anesthesia for Tooth Extractions
Author Information
Author(s): Henning Staedt, Victor Palarie, Diana Heimes, Peter Ottl, Shengchi Fan, Peer W. Kämmerer, Raffaele Capasso
Primary Institution: Nicolae Testemitanu State University of Medicine and Pharmacy, Moldova
Hypothesis
Buffered 4% articaine will provide better pain management and anesthesia efficacy compared to non-buffered 4% articaine during maxillary third molar extractions.
Conclusion
Buffered 4% articaine significantly reduces injection and post-extraction pain while enhancing the onset and duration of anesthesia compared to non-buffered articaine.
Supporting Evidence
- Buffered articaine significantly reduced injection pain compared to non-buffered articaine.
- Post-extraction pain was lower in the buffered group.
- The onset of anesthesia was faster with buffered articaine.
- The duration of anesthesia was longer with buffered articaine.
Takeaway
Using a special buffered version of articaine makes dental injections hurt less and helps the numbing medicine work faster and last longer.
Methodology
A randomized, double-blind, split-mouth study comparing buffered and non-buffered 4% articaine in 50 adult participants undergoing maxillary third molar extractions.
Potential Biases
No significant bias risks were reported; the study maintained a double-blind design.
Limitations
The study's sample was predominantly younger adults, limiting the generalizability of findings to older populations.
Participant Demographics
50 adults (23 males and 27 females) with a mean age of 21.6 years.
Statistical Information
P-Value
0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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