Reply: Changes in BMI after treatment of testicular cancer are due to age and hormonal function and not chemotherapy
2003

Impact of Treatment on BMI in Testicular Cancer Survivors

publication Evidence: moderate

Author Information

Author(s): Nord C, Fosså S D

Primary Institution: Department of Clinical Research, The Norwegian Radiumhospital

Hypothesis

Does chemotherapy influence BMI changes in survivors of testicular cancer?

Conclusion

Young survivors of testicular cancer, especially after chemotherapy, are at risk of excessive annual BMI increase compared to the normal population.

Supporting Evidence

  • The study showed no influence of chemotherapy on BMI compared to healthy controls.
  • Chemotherapy explained only 8% of the observations regarding BMI increase.
  • The surgery group displayed no significant annual BMI increase.

Takeaway

This study found that young men who survived testicular cancer might gain weight faster than other young men, especially if they had chemotherapy.

Methodology

Multivariate regression analysis comparing BMI changes in testicular cancer survivors to healthy controls.

Limitations

Few explanatory factors were included in the regression analysis, such as gonadal hormones, smoking, exercise, and eating habits.

Participant Demographics

Young survivors of testicular cancer.

Statistical Information

P-Value

0.013

Statistical Significance

p=0.013

Digital Object Identifier (DOI)

10.1038/sj.bjc.6601179

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