Comparative Clinical Study on Magnesium Absorption and Side Effects After Oral Intake of Microencapsulated Magnesium (MAGSHAPETM Microcapsules) Versus Other Magnesium Sources
2024

Study on Magnesium Absorption from Microencapsulated Magnesium Compared to Other Sources

Sample size: 40 publication 10 minutes Evidence: moderate

Author Information

Author(s): Pajuelo David, Meissner Justyna M., Negra Teresa, Connolly Alan, Mullor Jose L.

Primary Institution: Bionos Biotech SL

Hypothesis

The study aims to assess the plasma magnesium levels after oral administration of MAGSHAPETM microcapsules compared to other magnesium sources.

Conclusion

MAGSHAPETM microcapsules are a bioavailable and well-tolerated alternative to existing magnesium-based ingredients used in food supplements.

Supporting Evidence

  • The microencapsulation technology significantly increased magnesium bioavailability compared to non-microencapsulated magnesium oxide.
  • Mg-MS showed a sustained increase in plasma magnesium levels over 6 hours.
  • Participants reported fewer side effects with Mg-MS compared to other magnesium sources.

Takeaway

This study found that a new type of magnesium supplement works better and causes fewer tummy troubles than other types.

Methodology

A double-blind, randomized, cross-over clinical study with blood samples taken before and after the intake of different magnesium sources.

Potential Biases

Potential bias due to the funding from Lubrizol Life Science, which provided the products used in the study.

Limitations

The study only included healthy volunteers and did not assess populations with magnesium deficiencies.

Participant Demographics

40 healthy volunteers aged 20-55, men and women of all races/ethnicities, with a BMI of 18-35 kg/m2.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/nu16244367

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