Effect of Resident Physician Education Regarding Selective Chemoprophylaxis for the Prevention of Early Onset Group B Streptococcal Sepsis: An Outcome Study
1994

Effect of Resident Physician Education on Group B Streptococcal Sepsis Prevention

Sample size: 28334 publication Evidence: low

Author Information

Author(s): Jeffrey S. Greenspoon, Doron J.D. Rosen, Anita P. Sumen

Primary Institution: Cedars-Sinai Medical Center

Hypothesis

Does a resident education program for selective chemoprophylaxis reduce the incidence of early onset group B streptococcal sepsis?

Conclusion

The education program did not significantly reduce the incidence of early onset group B streptococcal sepsis.

Supporting Evidence

  • The incidence of GBS EOS was 0.05% before and 0.064% after the education program.
  • Compliance with chemoprophylaxis was voluntary and not consistently monitored.
  • Some cases of GBS EOS occurred in infants without risk factors.

Takeaway

Teaching doctors about preventing a type of infection in newborns didn't help lower the number of babies getting sick.

Methodology

The study reviewed cases of GBS EOS before and after a resident education program over two 2-year periods.

Potential Biases

Potential bias due to voluntary compliance with chemoprophylaxis recommendations.

Limitations

The study did not determine the compliance rate with chemoprophylaxis among patients with risk factors.

Participant Demographics

Participants included pregnant women at an urban, university-affiliated community hospital.

Statistical Information

Confidence Interval

95% CI -0.071% to 0.04%

Statistical Significance

P not significant

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