Effects of Green Tea and Licorice on Thyroid Function in Rats
Author Information
Author(s): El Mgeed A Abd, Bstawi M, Mohamed U, Gabbar M Abdel
Primary Institution: Cairo University, Egypt
Hypothesis
The study investigates the histopathological and biochemical effects of green tea and/or licorice aqueous extracts on thyroid functions in male albino rats intoxicated with dimethylnitrosamine.
Conclusion
Aqueous extract of green tea may be effective in amelioration of biochemical effects and histopathological lesions induced by DMN.
Supporting Evidence
- DMN intoxication caused significant changes in thyroid hormone levels.
- Green tea administration improved T3 and T4 levels compared to DMN alone.
- Licorice did not significantly affect T3 and T4 levels but increased TSH levels.
Takeaway
This study looked at how green tea and licorice can help rats with thyroid problems caused by a harmful chemical. Green tea seemed to help the rats feel better.
Methodology
40 male albino rats were divided into normal and DMN-intoxicated groups, with various treatments over 4 weeks, followed by biochemical and histopathological assessments.
Participant Demographics
Male albino rats
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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