Barcelona-ASymptomatic Intracranial Atherosclerosis Study (ASIA): Rationale and Design
Author Information
Author(s): López-Cancio Elena, Dorado Laura, Millán Mónica, Reverté Silvia, Suñol Anna, Massuet Anna, Mataró María, Galán Amparo, Alzamora Maite, Pera Guillem, Torán Pere, Dávalos Antoni, Arenillas Juan F
Primary Institution: Hospital Universitari Germans Trias I Pujol, Universitat Autònoma de Barcelona
Hypothesis
What is the prevalence and natural history of asymptomatic intracranial atherosclerosis in Caucasians?
Conclusion
The ASIA study aims to determine the prevalence of asymptomatic intracranial atherosclerosis and its impact on future ischemic events.
Supporting Evidence
- Intracranial atherosclerosis is a major cause of ischemic stroke worldwide.
- Early detection of asymptomatic intracranial atherosclerosis may allow for therapeutic intervention.
- The prevalence of asymptomatic intracranial atherosclerosis in Caucasians is currently unknown.
Takeaway
This study is trying to find out how many people have a type of artery blockage in their brains that doesn't cause symptoms yet, so doctors can help them before it becomes a problem.
Methodology
Population-based, prospective, long-term follow-up observational study with a cross-sectional and longitudinal phase.
Limitations
The study may have a 10% exclusion rate and a 20% non-acceptance rate among selected participants.
Participant Demographics
Caucasian population with moderate-high vascular risk, aged over 50 years.
Digital Object Identifier (DOI)
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