Using Cord Blood Platelet-Rich Plasma for Cesarean Section Wound Healing
Author Information
Author(s): Thanachaiviwat Amornrat, Suthaporn Sutham, Teng-umnuay Patana
Primary Institution: Police General Hospital, Bangkok, Thailand
Hypothesis
Cord blood platelet-rich plasma (CB-PRP) would provide beneficial effects in terms of wound healing and pain reduction in women undergoing cesarean section.
Conclusion
CB-PRP potentially promotes wound healing following cesarean sections but does not reduce pain.
Supporting Evidence
- CB-PRP group had a significantly lower REEDA score on postoperative day 1 compared to the control group.
- VSS was significantly lower in the CB-PRP group at postoperative week 8.
- Pain reduction was not significantly different between the two groups.
Takeaway
This study looked at a special treatment using blood from the umbilical cord to help heal wounds after a cesarean section, and it found that it helps wounds heal better but doesn't help with pain.
Methodology
This study is a randomized controlled trial involving 52 pregnant women who underwent cesarean sections, with participants assigned to either the intervention group (CB-PRP) or the control group.
Potential Biases
The study was not double-blind, which may introduce bias.
Limitations
The study had a small sample size and a short follow-up period of 8 weeks.
Participant Demographics
All participants were pregnant women undergoing cesarean sections.
Statistical Information
P-Value
p=0.009
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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