Critical Review of Aging Clocks and Factors Influencing Aging
Author Information
Author(s): Min Mildred, Egli Caitlin, Dulai Ajay S., Sivamani Raja K.
Primary Institution: Integrative Research Institute, Sacramento, CA, United States
Conclusion
Aging clocks have significant therapeutic potential to better understand aging and the influence of chronic inflammation and diseases in an expanding older population.
Supporting Evidence
- Aging clocks utilize various biological markers to estimate aging rates.
- Research shows that lifestyle factors significantly influence aging outcomes.
- Different aging clocks have been developed based on epigenetic, proteomic, and microbiome changes.
Takeaway
Aging clocks are tools that help us understand how quickly we age based on different biological markers, and they can help improve health as we get older.
Methodology
The review involved a literature search on PubMed/MEDLINE databases using various keywords related to aging clocks and biological age.
Potential Biases
Potential bias due to under-representation of diverse populations in aging clock studies.
Limitations
Limitations include technical noise in aging clocks and variability in the applicability of samples used.
Participant Demographics
The review included studies with participants ranging from children to older adults, but specific demographics were not detailed.
Digital Object Identifier (DOI)
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