Persistent Symptoms in Children After COVID-19 Hospitalization
Author Information
Author(s): Conde Marta, Gastesi Irati, de Pablo Lucía, Villanueva-Medina Sara, Aguilera-Alonso David, Esteban Ana, Epalza Cristina, López María, Domínguez-Rodríguez Sara, Gómez Pablo, Ballesteros Álvaro, Pinto Carlota, Navarro Marisa, Giaquinto Carlo, Moraleda Cinta, Tagarro Alfredo
Primary Institution: Fundación para la Investigación Biomédica e Innovación Hospital Universitario Infanta Sofía y del Henares (FIIB HUIS HHEN)
Hypothesis
What is the prevalence and characteristics of persistent symptoms in children hospitalized for acute COVID-19 compared to those hospitalized for other conditions?
Conclusion
There is no significant difference in the prevalence of persistent symptoms one year after hospitalization between children with acute COVID-19 and those hospitalized for other conditions.
Supporting Evidence
- 35% of children in the study had persistent symptoms one year after hospitalization.
- 28% of COVID-19 participants had symptoms that persisted for 12 months.
- Readmissions occurred in 22% of COVID-19 participants compared to 13% of non-COVID-19 participants.
Takeaway
This study looked at kids who were in the hospital for COVID-19 and found that many still had symptoms a year later, but it was similar to kids who were in the hospital for other reasons.
Methodology
An observational study comparing children hospitalized for acute COVID-19 with a control group hospitalized for other conditions, using clinical records and standardized questionnaires.
Potential Biases
The choice of non-COVID-19 participants might have influenced the persistent symptoms reported.
Limitations
The study may be underpowered due to a small sample size and potential selection bias.
Participant Demographics
The study included children aged 1 month to 18 years, with 58.3% assigned male sex at birth.
Statistical Information
P-Value
0.140
Confidence Interval
95% CI: 1.75; 15.6
Statistical Significance
p = 0.140
Digital Object Identifier (DOI)
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