Persistent Symptoms (Lasting Longer than 1 Year) in Children Hospitalized with Acute COVID-19 Versus Other Conditions
2024

Persistent Symptoms in Children After COVID-19 Hospitalization

Sample size: 96 publication 10 minutes Evidence: moderate

Author Information

Author(s): Conde Marta, Gastesi Irati, de Pablo Lucía, Villanueva-Medina Sara, Aguilera-Alonso David, Esteban Ana, Epalza Cristina, López María, Domínguez-Rodríguez Sara, Gómez Pablo, Ballesteros Álvaro, Pinto Carlota, Navarro Marisa, Giaquinto Carlo, Moraleda Cinta, Tagarro Alfredo

Primary Institution: Fundación para la Investigación Biomédica e Innovación Hospital Universitario Infanta Sofía y del Henares (FIIB HUIS HHEN)

Hypothesis

What is the prevalence and characteristics of persistent symptoms in children hospitalized for acute COVID-19 compared to those hospitalized for other conditions?

Conclusion

There is no significant difference in the prevalence of persistent symptoms one year after hospitalization between children with acute COVID-19 and those hospitalized for other conditions.

Supporting Evidence

  • 35% of children in the study had persistent symptoms one year after hospitalization.
  • 28% of COVID-19 participants had symptoms that persisted for 12 months.
  • Readmissions occurred in 22% of COVID-19 participants compared to 13% of non-COVID-19 participants.

Takeaway

This study looked at kids who were in the hospital for COVID-19 and found that many still had symptoms a year later, but it was similar to kids who were in the hospital for other reasons.

Methodology

An observational study comparing children hospitalized for acute COVID-19 with a control group hospitalized for other conditions, using clinical records and standardized questionnaires.

Potential Biases

The choice of non-COVID-19 participants might have influenced the persistent symptoms reported.

Limitations

The study may be underpowered due to a small sample size and potential selection bias.

Participant Demographics

The study included children aged 1 month to 18 years, with 58.3% assigned male sex at birth.

Statistical Information

P-Value

0.140

Confidence Interval

95% CI: 1.75; 15.6

Statistical Significance

p = 0.140

Digital Object Identifier (DOI)

10.3390/children11121444

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