Fusion beat in patients with heart failure treated with left ventricular pacing: may ECG morphology relate to mechanical synchrony? A pilot study
2008

Using ECG to Optimize Heart Failure Treatment with Pacing

Sample size: 24 publication Evidence: moderate

Author Information

Author(s): Gianfranchi Lorella, Bettiol Katia, Sassone Biagio, Verlato Roberto, Corbucci Giorgio, Alboni Paolo

Primary Institution: Ospedale di Cento

Hypothesis

Can QRS morphology be used to optimize device programming in heart failure patients treated with left ventricular pacing?

Conclusion

ECG criteria based on the fusion band may help optimize resynchronization therapy in heart failure patients.

Supporting Evidence

  • Diastolic filling time and myocardial performance index showed significant improvement in the fusion band.
  • Interventricular delay and mitral regurgitation decreased significantly as AV delay shortened.
  • Using ECG to identify the fusion band can help optimize pacing settings for better heart function.

Takeaway

Doctors can use special heart wave patterns to help patients with heart failure feel better when they get treated with pacing.

Methodology

Patients underwent CRT device implantation and were evaluated with echocardiography and ECG to assess the fusion band.

Limitations

The study was conducted at rest and did not evaluate dynamic behavior during exercise or compare ischemic and non-ischemic subgroups.

Participant Demographics

{"age":"66 ± 10 years","males":"15 (63%)","females":"9 (37%)","NYHA_class":"2.73 ± 0.46","EF":"28 ± 5%"}

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-7120-6-1

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