Dumping Syndrome After Esophageal Cancer Surgery
Author Information
Author(s): Lin Yuan MPH, Wang Hejie MSc, Qu Yaxin MPH, Liu Zhiqiang PhD, Lagergren Pernilla PhD, Xie Shao-Hua PhD
Primary Institution: Fujian Medical University
Hypothesis
What is the prevalence of dumping syndrome after esophageal cancer surgery?
Conclusion
Dumping syndrome is common after esophageal cancer surgery, with a pooled prevalence of 27%.
Supporting Evidence
- The prevalence of dumping syndrome ranged from 0% to 74% across studies.
- The pooled prevalence was 27% with high heterogeneity (I2 = 99%).
- Studies using specialized questionnaires reported a higher prevalence of 67%.
- Prevalence varied by year of publication and study population.
- More accurate measurement methods are needed for future studies.
Takeaway
After surgery for esophageal cancer, many patients can feel sick quickly after eating, which is called dumping syndrome.
Methodology
A systematic review and meta-analysis of 16 studies were conducted to estimate the prevalence of dumping syndrome.
Potential Biases
Some studies had concerns regarding methodological quality.
Limitations
High heterogeneity across studies and limited accuracy in subgroup analyses due to the small number of studies.
Participant Demographics
The studies included 2240 patients, with varying male percentages and age ranges.
Statistical Information
P-Value
0.0010
Confidence Interval
95% CI 14–39%
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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