Surgical Shunting of Pancreatic Blood in Diabetics
Author Information
Author(s): E.I. Galperin, T.G. Diuzheva, P.F. Petrovsky, A. Yu. Chevokin, K.V. Dokuchayev, S.E. Rabinovich, E.P. Gitel, N.F. Kuzovlev, L.V. Platonova
Primary Institution: I.M. Sechenov Medical Academy, Moscow, Russia
Hypothesis
The long-term results of pancreatic blood shunting depend on the patency of the splenorenal anastomosis.
Conclusion
Patients with patent anastomoses showed significant improvements in glycosylated hemoglobin levels and reduced insulin requirements.
Supporting Evidence
- Anastomotic patency was found in 114 patients, leading to significant clinical improvements.
- Patients with patent anastomoses had a decrease in glycosylated hemoglobin from 13.3% to 9.3%.
- Insulin doses were reduced from 0.97 U/kg to 0.72 U/kg in patients with patent anastomoses.
- Pain in lower extremities disappeared in 52 patients with patent anastomoses.
- Glucagon levels increased from 60.8 pg/ml to 91.5 pg/ml in patients with patent anastomoses.
Takeaway
Doctors found that a new surgery to redirect blood from the pancreas can help people with diabetes feel better and need less insulin.
Methodology
The study involved angiographic examinations and follow-ups of 137 patients who underwent pancreatic blood shunting surgery.
Limitations
The study did not include patients who declined angiography, which may affect the generalizability of the results.
Participant Demographics
Patients aged 16 to 52 years, median age 29.5 years, with a duration of diabetes from 1.5 to 27 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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