Loss-adjusted survival of cervix cancer in Khon Kaen, Northeast Thailand
2004

Survival of Cervix Cancer in Northeast Thailand

Sample size: 601 publication Evidence: moderate

Author Information

Author(s): Sriamporn S, Swaminathan R, Parkin D M, Kamsa-ard S, Hakama M

Primary Institution: Khon Kaen University

Hypothesis

Can loss to follow-up affect the survival estimates of cervix cancer patients?

Conclusion

The study found that loss to follow-up leads to an underestimation of survival rates in cervix cancer patients.

Supporting Evidence

  • 83% of patients were diagnosed microscopically.
  • 27.6% of cases were lost to follow-up over 5 years.
  • Patients aged under 40 had the best survival rates.
  • Stage I patients had a 5-year survival rate of 74.6%.
  • Patients who received treatment had better survival rates than those who did not.

Takeaway

This study looked at how many women with cervix cancer survived over five years and found that losing track of some patients made it seem like more survived than actually did.

Methodology

The study used a population-based cancer registry and followed patients for up to 10 years, applying both actuarial and loss-adjusted survival methods.

Potential Biases

There is a risk of bias due to differential loss to follow-up, particularly among patients with poorer prognoses.

Limitations

The study may not account for all factors influencing loss to follow-up, and the results may not be generalizable to other regions.

Participant Demographics

The study included 601 women diagnosed with cervix cancer, with a significant proportion under 50 years old and varying stages of disease.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6601959

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