Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing
2012

Honey Hydrogel for Burn Wound Healing

Sample size: 96 publication 10 minutes Evidence: high

Author Information

Author(s): Mohd Zohdi Rozaini, Abu Bakar Zakaria Zuki, Yusof Norimah, Mohamed Mustapha Noordin, Abdullah Muhammad Nazrul Hakim

Primary Institution: Universiti Putra Malaysia

Hypothesis

Can a honey-based hydrogel dressing improve burn wound healing compared to standard treatments?

Conclusion

The honey hydrogel dressing significantly enhanced wound healing and reduced inflammation in burn wounds.

Supporting Evidence

  • Honey hydrogel significantly enhanced wound closure compared to control treatments.
  • A decrease in inflammatory response was observed as early as 7 days after treatment.
  • Honey hydrogel modulated proinflammatory cytokines, aiding in wound healing.

Takeaway

This study shows that using a special honey gel can help heal burns faster and better than regular treatments.

Methodology

The study involved 96 rats with burn wounds treated with honey hydrogel, control hydrogel, and Opsite film dressing, with evaluations at multiple time points.

Limitations

The study was conducted on rats, which may not fully represent human responses.

Participant Demographics

Male Sprague-Dawley rats, weight 200–300 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2012/843025

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