The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma
2011

Eosinophilic Gastroenteritis in Asthma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Nair Parameswaran, Ochkur Sergei I, Protheroe Cheryl, Simms Elizabeth, Lee Nancy A, Lee James J

Primary Institution: Firestone Institute for Respiratory Health, St. Joseph's Healthcare and Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Hypothesis

Can eosinophilic gastroenteritis be identified in patients with eosinophilic bronchitis and asthma using a novel monoclonal antibody?

Conclusion

The study highlights a unique association of eosinophilic gastroenteritis with eosinophilic bronchitis and asthma, and the utility of a novel monoclonal antibody for diagnosis.

Supporting Evidence

  • The patient had a history of asthma and eosinophilia.
  • Use of a novel monoclonal antibody improved diagnostic accuracy for eosinophilic inflammation.
  • Symptoms included cough, wheeze, and gastrointestinal issues.

Takeaway

This case shows that a woman with asthma and stomach issues had a special kind of inflammation that doctors could see better with a new test.

Methodology

The case report describes a diagnostic protocol and the use of a monoclonal antibody to identify eosinophilic inflammation.

Limitations

The findings are based on a single case, limiting generalizability.

Participant Demographics

A 23-year-old woman with a history of asthma and eosinophilia.

Digital Object Identifier (DOI)

10.1186/1710-1492-7-4

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