Effect of a Semisolid Formulation of Linum usitatissimum L. (Linseed) Oil on the Repair of Skin Wounds
2012

Linseed Oil's Effect on Skin Wound Healing

Sample size: 72 publication Evidence: moderate

Author Information

Author(s): Franco Eryvelton de Souza, de Aquino Camilla Maria Ferreira, de Medeiros Paloma Lys, Evêncio Liriane Baratella, Góes Alexandre José da Silva, Maia Maria Bernadete de Souza

Primary Institution: Federal University of Pernambuco

Hypothesis

The study investigates the effects of a semisolid formulation of linseed oil on skin wounds in rats.

Conclusion

Topical administration of low concentrations of linseed oil significantly promotes reepithelialization in skin wounds.

Supporting Evidence

  • Groups treated with 1% or 5% SSFLO showed significant reepithelialization by day 6.
  • 100% reepithelialization was observed in treated animals by day 14.
  • Significant reduction in wound contraction was noted in linseed oil treated groups compared to controls.

Takeaway

Using a special linseed oil on cuts helps them heal faster and better.

Methodology

The study used incisional and excisional wound models on Wistar rats to evaluate the effects of different concentrations of linseed oil.

Limitations

The study was limited to animal models and may not directly translate to human healing.

Participant Demographics

Wistar rats (males and females, 200–300 g)

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2012/270752

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