Enhancing the Integration of Pre-Emptive Pharmacogenetic (PGx) Testing in Primary Care: Prioritizing Underserved Patients’ Preferences in Implementation
2024

Improving Pharmacogenetic Testing in Primary Care for Underserved Patients

Sample size: 25 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bryan Emma G., Lunsford Kelsey, Mullis Michaela D., McFarlane Antionette, Elwood Erica, Gawronski Brian E., Duarte Julio D., Fisher Carla L., Lee Su-Jun, Myers Alan L.

Primary Institution: University of Florida

Hypothesis

What are the preferences of patients who have experienced pharmacogenetic testing to inform its implementation in primary care?

Conclusion

Patients prefer pre-emptive pharmacogenetic testing as it is proactive, expedites treatment, and is convenient.

Supporting Evidence

  • Patients supported pre-emptive testing for being proactive about future health needs.
  • Participants valued having immediate access to medications while avoiding side effects.
  • Patients expressed a need for clear communication from clinicians regarding their test results.

Takeaway

This study found that patients like getting genetic tests done before they need medication, so doctors can help them faster and avoid bad side effects.

Methodology

Qualitative study using thematic analysis of interviews with 25 primary care patients from clinics serving medically underserved populations.

Limitations

The sample was predominantly female and lacked racial diversity, which may limit generalizability.

Participant Demographics

{"gender_distribution":{"female":19,"male":6},"age_range":"38-77","average_age":60,"racial_distribution":{"White":13,"Black":11,"Mixed Race":1},"employment_status":{"not_employed":20,"retired":11,"disabled":9},"education_level":{"high_school_or_less":8,"some_college_or_associate_degree":15},"income":{"42k_or_less":56}}

Digital Object Identifier (DOI)

10.3390/jpm14121128

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