Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis
2008

Detecting Depression in Cancer Patients with Simple Questions

Sample size: 1579 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mitchell A J

Primary Institution: Department of Cancer & Molecular Medicine, Leicester Royal Infirmary

Hypothesis

Can one or two simple verbal questions effectively detect depression in cancer and palliative care settings?

Conclusion

The study found that while simple verbal questions can help rule out depression, they are not reliable for confirming a diagnosis.

Supporting Evidence

  • A single depression question detected 72% of true cases but missed some.
  • The two-question method was significantly more accurate than either single question.
  • Simple verbal methods perform well at excluding depression in non-depressed patients.

Takeaway

This study looked at whether asking just one or two questions can help doctors find out if cancer patients are depressed. It turns out these questions can help, but they aren't perfect.

Methodology

The study conducted a systematic literature search and pooled analysis of 17 studies examining the effectiveness of verbal questions in detecting depression.

Potential Biases

The reliance on self-reported measures may introduce bias, as patients might underreport symptoms.

Limitations

The study highlights that no method achieved a case-finding accuracy of more than 60%, indicating potential for false positives.

Participant Demographics

The studies included a mix of cancer patients, with some in late-stage palliative care and others in mixed or early stages.

Statistical Information

P-Value

0.045

Confidence Interval

95% CI 66.3–76.8%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604396

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