Survival Factors for Oral and Pharyngeal Cancer in Taiwan
Author Information
Author(s): Chen Ping-Ho, Shieh Tien-Yu, Ho Pei-Shan, Tsai Chi-Cheng, Yang Yi-Hsin, Lin Ying-Chu, Ko Min-Shan, Tsai Pei-Chien, Chiang Shang-Lun, Tu Hung-Pin, Ko Ying-Chin
Primary Institution: National Health Research Institutes, Kaohsiung, Taiwan
Hypothesis
The study aims to identify the role of prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan.
Conclusion
The study found that ethnic groups, period of diagnosis, gender, diagnostic age, anatomic site, morphologic type, and therapy are significant predictive factors for survival in oral and pharyngeal carcinoma.
Supporting Evidence
- The five-year survival rates were significantly poorer for Hokkien and Taiwanese aborigines compared to Hakka.
- Males had significantly poorer prognosis than females.
- Subjects with tongue and/or mouth carcinoma presented the worst prognosis.
Takeaway
This study looked at how different factors like age, gender, and ethnicity affect how long people survive after being diagnosed with mouth and throat cancer in Taiwan.
Methodology
The study analyzed Taiwan Cancer Registry records of 9039 subjects diagnosed with oral and pharyngeal carcinoma, using Kaplan-Meier methods and Cox multivariate proportional hazards model.
Potential Biases
Potential misclassification of ethnic groups based on residential areas.
Limitations
Clinical carcinoma stage data was unavailable, and ethnicity was not clearly defined in the registry.
Participant Demographics
The study included Taiwanese aborigines, Hakka, and Hokkien communities, with a higher proportion of males diagnosed.
Statistical Information
P-Value
p<0.0001
Confidence Interval
95%CI, 0.86–1.33
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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