Expression of myriapod pair rule gene orthologs
2011

Expression of Myriapod Pair Rule Gene Orthologs

publication Evidence: moderate

Author Information

Author(s): Ralf Janssen, Graham E Budd, Nikola-Michael Prpic, Wim G M Damen

Primary Institution: Uppsala University, Department of Earth Sciences, Palaeobiology

Hypothesis

The study investigates the expression and function of pair rule gene orthologs in the pill millipede Glomeris marginata to understand their role in segmentation.

Conclusion

The pair rule gene network is partially conserved among insects and myriapods, indicating that some aspects of PRG interaction are convergent even within the Myriapoda.

Supporting Evidence

  • The expression of pair rule genes in Glomeris marginata suggests a role in segmentation.
  • PRG orthologs are expressed in segmental stripes during trunk segmentation.
  • Some PRG interactions are conserved between insects and myriapods.

Takeaway

This study looks at how certain genes help form segments in millipedes, showing that some gene patterns are similar to those in insects.

Methodology

The study involved gene cloning, RNA isolation, cDNA synthesis, and in situ hybridization to analyze gene expression patterns.

Limitations

The study lacks functional data to confirm the roles of the PRGs in segmentation.

Digital Object Identifier (DOI)

10.1186/2041-9139-2-5

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