Methylphenidate-Induced Mania-Like Symptoms in a Child
Author Information
Author(s): Kaustav Chakraborty, Sandeep Grover
Primary Institution: Institute of Neurosciences, Kolkata
Hypothesis
Can methylphenidate cause mania-like symptoms in children with ADHD and mental retardation?
Conclusion
Methylphenidate can induce mania-like symptoms in children, particularly those with comorbid ADHD and mental retardation.
Supporting Evidence
- Methylphenidate is known to cause adverse effects like psychosis or mania in a small number of cases.
- The incidence of stimulant-induced psychosis/mania is reported to be 1.48 per 100 person-years.
- The symptoms of adverse drug effect typically resolve within 2 to 7 days after stopping the medication.
Takeaway
A girl with ADHD took a medicine called methylphenidate and started acting very hyper and upset, so doctors had to give her other medicines to help her feel better.
Methodology
Case report of an 11-year-old girl treated with methylphenidate who developed mania-like symptoms.
Potential Biases
Potential bias due to reliance on a single case report.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
11-year-old girl with ADHD and moderate mental retardation.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website