Protein-Enriched Meal Replacements for Weight Loss
Author Information
Author(s): Leo Treyzon, Steve Chen, Kurt Hong, Eric Yan, Catherine L Carpenter, Gail Thames, Susan Bowerman, He-Jing Wang, Robert Elashoff, Zhaoping Li
Primary Institution: UCLA Center for Human Nutrition, Department of Medicine, David Geffen School of Medicine at UCLA
Hypothesis
Increasing the protein content of a meal replacement will result in increased weight loss and improved retention of lean body mass compared to a standard protein meal replacement.
Conclusion
Higher protein meal replacements resulted in similar overall weight loss as standard protein meal replacements, but with significantly more fat loss in the high protein group.
Supporting Evidence
- Both high protein and standard protein meal replacements were well tolerated with no adverse effects.
- Subjects in the high protein group lost significantly more fat weight than those in the standard protein group.
- There were no significant differences in overall weight loss between the two groups.
Takeaway
This study looked at whether adding more protein to meal replacement shakes helps people lose weight better. It found that while people lost weight, the extra protein didn't make a big difference in how much weight they lost overall.
Methodology
A single blind, placebo-controlled, randomized trial comparing high protein and standard protein meal replacements in 100 obese adults over 12 weeks.
Potential Biases
Potential bias due to self-reported compliance and the single-blind design.
Limitations
The study's results may have been influenced by participant compliance and the use of meal replacements, which could obscure the effects of protein enrichment.
Participant Demographics
100 obese men and women, mean age 49.4 years, BMI between 27 to 40 kg/m2.
Statistical Information
P-Value
0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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