Organic Papers (E)-3-[4-(Dimethylamino)phenyl]-1-(2-methyl-4-phenylquinolin-3-yl)prop-2-en-1-one 0.7-hydrate
2011
Study of a New Chalcone Derivative
publication
Evidence: moderate
Author Information
Author(s): Loh Wan-Sin, Fun Hoong-Kun, Sarveswari S., Vijayakumar V., Prasath R.
Primary Institution: Universiti Sains Malaysia
Hypothesis
The study investigates the synthesis and crystal structure of a new chalcone derivative.
Conclusion
The new chalcone derivative exhibits a planar quinoline ring system and is stabilized by hydrogen bonds and π–π interactions in the crystal structure.
Supporting Evidence
- The quinoline ring system is approximately planar with a maximum deviation of 0.011 Å.
- Molecules are linked to water molecules via intermolecular hydrogen bonds.
- The crystal structure is stabilized by C—H⋯π interactions.
Takeaway
The researchers made a new type of chalcone and found that its structure is stable because of special bonds between its molecules.
Methodology
The compound was synthesized through a reaction of 3-acetyl-2-methyl-4-phenylquinoline and N,N-dimethylamino-benzaldehyde, followed by crystallization.
Digital Object Identifier (DOI)
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