Successful Fertility Preservation in a Case of Low-Grade Endometrial Stromal Sarcoma: A Multidisciplinary Approach Through the Oncofertility Network
2024

Successful Fertility Preservation in a Case of Low-Grade Endometrial Stromal Sarcoma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Ooi Katsuhiro, Wakimoto Yu, Oki Noriyoshi, Sakata Mina, Mabuchi Seiji

Primary Institution: Hyogo College of Medicine

Hypothesis

Can fertility be preserved in patients diagnosed with low-grade endometrial stromal sarcoma (LGESS) through a multidisciplinary approach?

Conclusion

The case demonstrates that fertility preservation is feasible in LGESS patients, leading to the successful birth of two children.

Supporting Evidence

  • The patient successfully gave birth to two healthy children after fertility preservation efforts.
  • The multidisciplinary approach through the Hyogo Oncofertility Network facilitated timely access to reproductive services.
  • High-dose progestin therapy was used to reduce the risk of cancer recurrence.

Takeaway

A woman with a rare cancer was able to have two babies before getting her surgery, thanks to special medical help that focused on both her cancer and her desire to be a mom.

Methodology

The patient underwent laparoscopic surgery, embryo cryopreservation using the DuoStim method, and hormone therapy to mitigate cancer recurrence.

Limitations

The study is based on a single case, limiting generalizability.

Participant Demographics

27-year-old nulligravida female with no prior medical history.

Digital Object Identifier (DOI)

10.7759/cureus.74539

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