Probiotics Reduce E. coli Attachment in Weaned Pigs
Author Information
Author(s): Daudelin Jean-François, Lessard Martin, Beaudoin Frédéric, Nadeau Éric, Bissonnette Nathalie, Boutin Yvan, Brousseau Jean-Philippe, Lauzon Karoline, Fairbrother John Morris
Primary Institution: Dairy and Swine Research and Development Centre, Agriculture and Agri-Food Canada
Hypothesis
The study aims to evaluate the effect of probiotics on E. coli attachment and cytokine expression in weaned pigs.
Conclusion
The administration of probiotics significantly reduced E. coli attachment to the ileal mucosa in weaned pigs.
Supporting Evidence
- Probiotics were administered daily during lactation and after weaning.
- Attachment of ETEC F4 to the intestinal mucosa was significantly reduced in pigs treated with probiotics.
- Proinflammatory cytokines were upregulated in ETEC F4 challenged pigs treated with probiotics.
Takeaway
Giving certain probiotics to baby pigs helps stop bad bacteria from sticking to their tummies, which can make them sick.
Methodology
40 Yorkshire-Landrace gilts were divided into five treatment groups, including probiotics and antibiotics, and challenged with E. coli.
Limitations
The study was limited to a specific age group of pigs and a single strain of E. coli.
Participant Demographics
Yorkshire-Landrace gilts, 28 days old at the time of challenge.
Statistical Information
P-Value
0.01 and 0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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