Evaluating Endoscopic Treatments for Sessile Serrated Lesions
Author Information
Author(s): Kagemoto Kaizo, Okamoto Koichi, Okada Yasuyuki, sei Motoko, Fujimoto Shota, Yagi Mai, Mitsuhashi Takeshi, Ueda Hiroyuki, Yoshimoto Takanori, Kashihara Takanori, Kawaguchi Tomoyuki, Kida Yoshifumi, Mitsui Yasuhiro, Kawano Yutaka, Sogabe Masahiro, Miyamoto Hiroshi, Sato Yasushi, Muguruma Naoki, Takayama Tetsuji
Primary Institution: Tokushima University Graduate School
Hypothesis
What is the most suitable endoscopic treatment for sessile serrated lesions (SSL)?
Conclusion
Underwater endoscopic mucosal resection (UEMR) is a suitable treatment option for sessile serrated lesions, while cold snare polypectomy (CSP) results were pathologically insufficient.
Supporting Evidence
- The R0 resection rate significantly differed among the three groups: EMR (73%), CSP (42%), UEMR (87%).
- The median thickness of submucosal tissue resected by CSP was significantly less than that by EMR and UEMR.
- All four SSLD cases received R0 resection by EMR and UEMR.
- CSP had a particularly low VM0 resection rate, indicating potential risks for incomplete resection.
Takeaway
Doctors are trying to find the best way to remove certain types of growths in the colon. They found that one method works better than others.
Methodology
This was a single-center retrospective study analyzing 92 sessile serrated lesions resected by EMR, CSP, and UEMR.
Potential Biases
Selection bias may exist due to the exclusion of fragmented or unstretched lesions.
Limitations
The study was conducted at a single institute with a small number of cases and utilized a retrospective design.
Participant Demographics
The study included 92 patients with a median age of 65 years, with no significant differences in age, gender, or lesion location among treatment groups.
Statistical Information
P-Value
0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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