Does Rubella Immunity Predict Measles Immunity in Pregnant Women?
Author Information
Author(s): Colleen M. Kennedy, Barbara A. Burns, Kevin A. Ault
Primary Institution: University of Iowa Hospitals and Clinics
Hypothesis
Does rubella immunity infer measles immunity in pregnant women?
Conclusion
Rubella immunity does not predict measles immunity in pregnant women.
Supporting Evidence
- 88% of women tested were immune to measles, while 98% were immune to rubella.
- 88% of those with rubella immunity were also measles immune.
- There was no association between rubella and measles immunity identified.
Takeaway
This study found that just because a pregnant woman is immune to rubella doesn't mean she is immune to measles.
Methodology
Stored serum samples were tested for rubella and measles immunities using IgG enzyme-linked immunosorbent assay.
Limitations
The study's findings may not be generalizable due to the sample being primarily from Caucasian pregnant women in the Midwest.
Participant Demographics
The average age of participants was 28 years, with a range from 14 to 44 years; the population was primarily non-Hispanic white.
Statistical Information
P-Value
<0.0001
Confidence Interval
95% CI 0.0314, 0.2392
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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