Carrot Fiber Boosts Healthy Gut Metabolite Production
Author Information
Author(s): Annick Mercenier, Dai Lam Vu, Jonas Poppe, Ruud Albers, Sue McKay, Pieter Van den Abbeele
Primary Institution: NutriLeads BV, Wageningen, The Netherlands
Hypothesis
Does carrot-derived rhamnogalacturonan-I (cRG-I) enhance the production of health-promoting metabolites by the gut microbiota?
Conclusion
Carrot-derived rhamnogalacturonan-I significantly increases the production of indole-3-propionic acid in the gut microbiota of humans.
Supporting Evidence
- cRG-I increased indole-3-propionic acid production by 45.8% at a dose of 1.5 g/d.
- At a lower dose of 0.3 g/d, cRG-I still increased indole-3-propionic acid production by 14.6%.
- The increase in indole-3-propionic acid levels correlated strongly with the abundance of Bifidobacterium longum.
Takeaway
Eating carrot fiber helps good bacteria in your tummy make a special substance that can keep you healthy.
Methodology
The study used ex vivo SIFR® technology and untargeted metabolite profiling to analyze the effects of cRG-I on gut microbiota from human fecal samples.
Potential Biases
Potential funding bias as the study was funded by NutriLeads, which holds patents for cRG-I.
Limitations
The study was conducted ex vivo, which may not fully replicate in vivo conditions.
Participant Demographics
24 healthy adults (13 males, 11 females) aged 25-65 years.
Statistical Information
P-Value
6.1 × 10−16
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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