Colorectal Cancer Risk and Lifestyle Factors
Author Information
Author(s): Nilsen T I Lund, Vatten L J
Primary Institution: Norwegian University of Science and Technology
Hypothesis
Hyperinsulinaemia may promote colorectal cancer.
Conclusion
The study found that physical activity is inversely associated with colorectal cancer risk in men, while diabetes and high blood glucose levels increase the risk in women.
Supporting Evidence
- The study followed 75,219 participants over 12 years.
- 730 cases of colorectal cancer were registered during the study.
- Men showed a negative association between leisure-time physical activity and colorectal cancer risk.
- Women with a history of diabetes had an increased risk of colorectal cancer.
- Women with non-fasting blood glucose levels ≥8.0 mmol l−1 were at higher risk of colorectal cancer.
Takeaway
Being active can help men avoid colorectal cancer, but women with diabetes or high blood sugar are at a higher risk.
Methodology
The study prospectively examined the association between colorectal cancer risk and factors related to insulin resistance and hyperinsulinaemia over 12 years.
Participant Demographics
Norwegian men and women.
Statistical Information
P-Value
0.002
Confidence Interval
95% CI = 0.37–0.79 for men; 95% CI = 1.04–2.31 for women with diabetes; 95% CI = 1.31–2.98 for women with high blood glucose.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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