The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer
1999

Fish Oil Supplement Helps Weight Gain in Pancreatic Cancer Patients

Sample size: 20 publication Evidence: moderate

Author Information

Author(s): Barber M D, Ross J A, Voss A C, Tisdale M J, Fearon K C H

Primary Institution: University Department of Surgery, Royal Infirmary of Edinburgh

Hypothesis

Can a combination of eicosapentaenoic acid (EPA) with a conventional oral nutritional supplement produce weight gain in patients with advanced pancreatic cancer?

Conclusion

The study found that patients with advanced pancreatic cancer gained weight after consuming a fish oil-enriched nutritional supplement.

Supporting Evidence

  • Patients were losing weight at a median rate of 2.9 kg month−1 at baseline.
  • After 3 weeks, patients gained a median of 1 kg and after 7 weeks, a median of 2 kg.
  • Dietary intake increased significantly by almost 400 kcal day−1.

Takeaway

Patients with pancreatic cancer who took a special fish oil drink gained weight, which is usually hard for them.

Methodology

Patients consumed two cans of a fish oil-enriched nutritional supplement daily and were assessed for weight and dietary intake.

Participant Demographics

Patients had unresectable pancreatic adenocarcinoma.

Statistical Information

P-Value

P = 0.024; P = 0.033; P = 0.002

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690654

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