THE STARTING A TESTOSTERONE AND EXERCISE PROGRAM AFTER HIP INJURY (STEP-HI) TRIAL: STUDY RESULTS AND IMPLICATIONS
2024

Testosterone and Exercise Program After Hip Injury Study Results

Sample size: 129 publication

Author Information

Author(s): Ellen Binder, Douglas Kiel

Primary Institution: Oxford University Press US

Hypothesis

Does a multi-modal intervention including testosterone and exercise improve functional outcomes in older female hip fracture patients?

Conclusion

The study found that a combination of supervised exercise and testosterone treatment may improve outcomes for older women recovering from hip fractures.

Supporting Evidence

  • Hip fractures are common among older women and can severely impact their independence.
  • Many women do not return to their pre-fracture level of function after a hip fracture.
  • Age-associated androgen deficiency may contribute to muscle mass and strength deficits in older female hip fracture patients.

Takeaway

This study looked at how exercise and testosterone can help older women who broke their hips get better and stronger.

Methodology

A three-group, randomized, double-blinded, placebo-controlled Phase III clinical trial conducted at 8 clinical sites.

Participant Demographics

129 female hip fracture patients, age 65 years and older.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0270

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