Patient and physician expectations regarding disease and treatment of advanced HCC: The prospective PERCEPTION1 study

2024

Patient and Physician Expectations in Advanced Liver Cancer

Sample size: 205 publication 10 minutes Evidence: moderate

Author Information

Author(s): Nault Jean-Charles, Sritharan Nanthara, Verset Gontran, Borbath Ivan, Lequoy Marie, Allaire Manon, Regnault Hélène, Colle Isabelle, Orlent Hans, Sinapi Isabelle, Moreno Christophe, Larrey Edouard, Sidali Sabrina, Hollande Clémence, Amaddeo Giuliana, Pol Stanislas, Nahon Pierre, Ganne-Carrié Nathalie, Levy Vincent, Bloch-Queyrat Coralie, Trepo Eric, Bouattour Mohammed

Primary Institution: Liver unit, Avicenne hospital, APHP Bobigny, France

Hypothesis

What are the differences in expectations regarding treatment and prognosis between patients and physicians in advanced hepatocellular carcinoma?

Conclusion

Expectations regarding systemic treatments for advanced HCC differ significantly between patients and physicians, showing notable variations across countries.

Supporting Evidence

60% of patients did not discuss life expectancy with their physician.
63% of patients believed they had a life expectancy greater than 5 years.
36.4% concordance was observed between patient and physician responses.
Patients from Belgium were more satisfied with consultations than those from France.
52% of patients showed symptoms of anxiety or depression.

Takeaway

Patients with advanced liver cancer often think they will live longer than their doctors believe, and there are big differences in how patients in France and Belgium feel about their treatment.