HALP Score and Treatment Response in Early-Stage Gastric Cancer
Author Information
Author(s): Köşeci Tolga, Seyyar Mustafa, Aydınalp Camadan Yasemin, Çelik Halil, Mete Burak, Demirhindi Hakan, Eser Kadir, Ata Serdar, Solmaz Ali Alper, Çil Timuçin
Primary Institution: Çukurova University
Hypothesis
The HALP score can predict the pathological response in early-stage gastric cancer patients undergoing perioperative treatment.
Conclusion
The HALP score is a useful and easily accessible tool for determining pathological responses in patients with locally advanced gastric cancer.
Supporting Evidence
- The HALP score cut-off was determined to be 28.9, with a pathological response probability of 64.8% for patients with scores above this threshold.
- Patients with high HALP scores had a median survival time of 45.4 months compared to 30.6 months for those with low scores.
- Pathological response rates were significantly higher in patients with HALP scores ≥ 28.9.
Takeaway
The HALP score helps doctors understand how well treatment is working for patients with stomach cancer, making it easier to predict their recovery.
Methodology
This retrospective cohort study analyzed 118 patients diagnosed with early-stage gastric cancer who received perioperative treatment between 2018 and 2023.
Potential Biases
The removal of patients due to incomplete data may introduce bias.
Limitations
The study's retrospective nature and potential bias from missing data.
Participant Demographics
The mean age of participants was 61.3 years, with a male-to-female ratio of 84 to 34.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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