Characterization of CetA and CetB, a bipartite energy taxis system in Campylobacter jejuni
2008

Study of CetA and CetB in Campylobacter jejuni

publication Evidence: moderate

Author Information

Author(s): Kathryn T. Elliott, Victor J. DiRita

Primary Institution: University of Michigan

Hypothesis

CetA and CetB interact to transduce an energy taxis signal.

Conclusion

CetA and CetB are co-transcribed and play a crucial role in energy taxis in Campylobacter jejuni.

Supporting Evidence

  • CetA and CetB are co-transcribed independently of the flagellar regulon.
  • CetB levels are dependent on CetA.
  • CetA is an integral membrane protein while CetB is a peripheral membrane protein.

Takeaway

CetA and CetB are two proteins in bacteria that help them move towards energy sources by sensing changes in their environment.

Methodology

The study involved molecular and biochemical characterization, including RT-PCR and Western blot analysis.

Digital Object Identifier (DOI)

10.1111/j.1365-2958.2008.06357.x

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