Overview of the Trending Enteric Viruses and Their Pathogenesis in Intestinal Epithelial Cell Infection
2024

Overview of Enteric Viruses and Their Effects on Intestinal Cells

publication Evidence: moderate

Author Information

Author(s): Chio Chi-Chong, Chien Jou-Chun, Chan Hio-Wai, Huang Hsing-I

Primary Institution: Chang Gung University

Hypothesis

What are the pathogenic mechanisms of trending enteric viruses in intestinal epithelial cells?

Conclusion

Enteric viral infections are a significant global health threat, causing severe gastrointestinal symptoms and potentially leading to systemic infections.

Supporting Evidence

  • Enteric viruses are transmitted via the fecal-oral route and primarily infect intestinal epithelial cells.
  • Diarrheal disease caused by enteric viruses is a leading cause of death in children under five years of age.
  • Some enteric viruses can invade other tissues, leading to severe conditions and even death.

Takeaway

Enteric viruses can make you very sick by infecting your stomach and intestines, causing symptoms like diarrhea and vomiting. They can also spread to other parts of the body and make you even sicker.

Methodology

This study is a literature review summarizing the pathogenic mechanisms of various enteric viruses.

Limitations

The review is limited by the lack of suitable infection models for some enteric viruses, particularly CV-A6 and human NoV.

Digital Object Identifier (DOI)

10.3390/biomedicines12122773

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