Lipid Lowering Effects of Amaranthus Caudatus in Rabbits
Author Information
Author(s): Kabiri Najmeh, Asgary Sedigheh, Setorki Mahbubeh
Primary Institution: Isfahan University
Hypothesis
Can hydroalcoholic extracts of Amaranthus caudatus induce regression of atherosclerotic lesions in rabbits on a high cholesterol diet?
Conclusion
The study suggests that hydroalcoholic extracts of A. caudatus can reduce risk factors and cause regression of fatty lesions in the aorta.
Supporting Evidence
- A. caudatus significantly decreased total cholesterol and LDL-cholesterol levels in treated rabbits.
- The atherosclerotic area was significantly decreased in rabbits treated with A. caudatus compared to those on a normal diet.
- Rabbits receiving only a normal diet showed progression of atherosclerosis.
Takeaway
This study found that a plant called Amaranthus can help make sick rabbits healthier by lowering their bad cholesterol and helping their hearts.
Methodology
Twenty-five rabbits were divided into five groups and treated with different diets for 75 days, with blood samples collected for biochemical analysis.
Participant Demographics
Male New Zealand white rabbits with an average body weight of 1.5-2 kg.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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