1,3-Bis[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-1H-benzimidazol-2(3H)-one
2011

Study of a New Compound with Oxazolidin-2-one Structure

publication Evidence: moderate

Author Information

Author(s): Ouzidan Younes, Kandri Rodi Youssef, Fronczek Frank R., Venkatraman Ramaiyer, El Ammari Lahcen, Essassi El Mokhtar

Primary Institution: Laboratoire de Chimie Organique Appliquée, Université Sidi Mohamed Ben Abdallah

Hypothesis

The synthesis of a new benzimidazol-2-one compound containing an oxazolidin-2-one ring will yield a stable molecular structure.

Conclusion

The synthesized compound exhibits a stable and planar molecular structure with specific geometric parameters.

Supporting Evidence

  • The compound's structure includes a central fused-ring system with nearly planar geometry.
  • Maximum deviations from the mean plane are minimal, indicating stability.
  • Two five-membered rings are linked to the central structure, contributing to its unique properties.

Takeaway

Scientists made a new chemical compound that has a special shape, which could be useful for making medicines.

Methodology

The compound was synthesized using a reaction involving 1H-benzo[d]imidazol-2(3H)-one and bis(2-chloroethyl)amine hydrochloride, followed by purification through column chromatography.

Digital Object Identifier (DOI)

10.1107/S1600536810052141

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