2-Methyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carbonitrile
2011
Study of 2-Methyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carbonitrile
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Rosli Mohd Mustaqim, Kumar D. J. Madhu, Prasad D. Jagadeesh, Nagaraja G. K.
Primary Institution: Universiti Sains Malaysia
Conclusion
The crystal structure of the compound shows that molecules form infinite chains through specific hydrogen-bond interactions.
Supporting Evidence
- The imidazo[1,2-a]pyridine group is planar with a maximum deviation of 0.021 Å.
- The F atoms in the trifluoromethyl group and the methyl H atoms are disordered over two sets of sites.
- Molecules are linked into infinite chains through C—H⋯N interactions.
Takeaway
This study looks at a chemical compound and how its molecules stick together in a special way, which might help in making medicines.
Methodology
X-ray crystallography was used to analyze the crystal structure of the compound.
Digital Object Identifier (DOI)
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