Lactate Dehydrogenase to Albumin Ratio as a Predictor of Fatal Outcomes in SFTS Patients
Author Information
Author(s): Meng Tao, Ding Wenqian, Lv Dongmei, Wang Chenxu, Xu Yuanhong
Primary Institution: The First Affiliated Hospital of Anhui Medical University, Hefei, China
Hypothesis
Can lactate dehydrogenase to albumin ratio (LAR) levels predict fatal outcomes in patients with severe fever with thrombocytopenia syndrome (SFTS)?
Conclusion
Elevated LAR levels on admission are an independent risk factor for fatal outcomes in patients with SFTS.
Supporting Evidence
- 209 patients with SFTS were analyzed in the study.
- Patients were divided into survival and deceased groups based on prognosis.
- The area under the ROC curve for LAR was 0.835, indicating strong predictive ability.
Takeaway
Doctors can use a simple blood test to check a number called LAR to see if a patient with a serious illness called SFTS might be in danger of dying.
Methodology
This observational study analyzed data from 209 patients with SFTS, comparing laboratory metrics and using Cox regression analyses to identify risk factors.
Potential Biases
Potential bias due to the retrospective nature of the study and variations in laboratory testing.
Limitations
The study is a single-center study, which may lead to selective bias, and laboratory tests were not identical for all patients.
Participant Demographics
Median age of participants was 64 years, with 42.1% male.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI, 0.773–0.896
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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