Rare Case of Sinus Bradycardia from Ondansetron
Author Information
Author(s): Moazzam Md Shahnawaz, Nasreen Farah, Bano Shahjahan, Amir Syed Hussain
Primary Institution: Frontier Lifeline & Dr K M Cherian Heart Foundation, Mogappair, Chennai, India
Hypothesis
Can intravenous ondansetron cause symptomatic sinus bradycardia?
Conclusion
Ondansetron can rarely cause symptomatic sinus bradycardia, which should be monitored during administration.
Supporting Evidence
- Ondansetron is effective for preventing nausea but can have rare cardiovascular side effects.
- The patient experienced severe bradycardia and respiratory arrest after ondansetron administration.
- After treatment with atropine, the patient's heart rate and blood pressure stabilized.
Takeaway
A woman had a slow heart rate after getting a medicine called ondansetron before surgery, which is usually safe.
Methodology
Case report of a 43-year-old female patient who experienced bradycardia after ondansetron administration.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
43-year-old female, ASA-I physical status, no prior cardiovascular issues.
Digital Object Identifier (DOI)
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