The interaction between sleep patterns and oxidative balance scores on the risk of cognitive function decline: Results from the national health and nutrition examination survey 2011–2014
2024

Sleep Patterns and Cognitive Decline Risk

Sample size: 2249 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lou Taiwei, Zhao Zhiru, Du Hongjin, Zhang Jiwei, Ni Tian, Wang Miaoran, Li Qiuyan

Primary Institution: Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China

Hypothesis

The study hypothesizes that oxidative balance scores (OBS) are related to cognitive decline and that sleep patterns and OBS jointly influence cognitive function.

Conclusion

Unhealthy sleep patterns and low oxidative balance scores increase the risk of cognitive decline in older adults.

Supporting Evidence

  • Long sleep duration is associated with a higher risk of poor cognitive performance.
  • Higher oxidative balance scores are linked to a lower risk of cognitive impairment.
  • Sleep patterns and oxidative balance scores can independently affect cognitive function.
  • Participants with long sleep duration and pro-oxidative factors have an increased risk of cognitive decline.

Takeaway

If older people sleep too much or too little and don't get enough antioxidants in their diet, they might have trouble thinking clearly.

Methodology

Data from 2249 adults aged 60 and older were analyzed using self-reported questionnaires and multivariable adjusted regression analyses.

Potential Biases

Self-reported data may introduce bias due to subjective interpretations of sleep patterns and cognitive function.

Limitations

The study is cross-sectional, which limits causal inferences, and relies on self-reported data that may be subjective.

Participant Demographics

Participants included 1,075 males and 1,174 females, with an average age of 68 years.

Statistical Information

P-Value

0.021

Confidence Interval

95% CI = 1.05–3.48

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0313784

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