Effect of Gymnema montanum Leaves on Lipids in Diabetic Rats
Author Information
Author(s): R. Ananthan, M. Latha, K. M. Ramkumar, L. Pari, C. Baskar, V. Narmatha Bai
Primary Institution: Bharathiar University
Hypothesis
The study aims to evaluate the effects of ethanolic extract of Gymnema montanum leaves on serum and tissue lipids in alloxan diabetic rats.
Conclusion
The ethanolic extract of Gymnema montanum leaves effectively reduces blood glucose and lipid levels in diabetic rats.
Supporting Evidence
- The extract at 200 mg/kg body weight was comparable to the reference drug glibenclamide.
- Treatment with GLEt significantly reduced lipid levels in diabetic rats.
- Increased plasma insulin levels were observed in diabetic rats treated with GLEt.
Takeaway
This study shows that a plant called Gymnema montanum can help lower sugar and fat levels in sick rats.
Methodology
Male Wistar rats were treated with different doses of ethanolic extract of Gymnema montanum leaves for 3 weeks, and various biochemical parameters were measured.
Limitations
The study was conducted only on male Wistar rats, which may limit the generalizability of the results.
Participant Demographics
Male Wistar rats, body weight of 180 to 200 g.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website