REEF: searching REgionally Enriched Features in genomes
2006
REEF: A Tool for Finding Enriched Genomic Features
Sample size: 896
publication
Evidence: moderate
Author Information
Author(s): Coppe Alessandro, Danieli Gian Antonio, Bortoluzzi Stefania
Primary Institution: Department of Biology, University of Padova
Hypothesis
Can we identify genomic regions enriched in specific features using a new software tool?
Conclusion
REEF can help understand how specific genomic regions contribute to their functional roles.
Supporting Evidence
- REEF identifies genomic regions enriched in specific features.
- The software is freely available for use.
- REEF can analyze any genome for local clustering of features.
Takeaway
REEF is a computer program that helps scientists find groups of genes that work together in specific parts of the genome.
Methodology
REEF uses a sliding window approach and the Hypergeometric Distribution to identify enriched genomic regions.
Limitations
The performance of REEF cannot be directly compared with other algorithms due to differences in aims and input data.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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