Risk stratification by CMR in Chagas' disease
2011

Risk Stratification in Chagas' Disease Using CMR

Sample size: 39 publication Evidence: moderate

Author Information

Author(s): Uellendahl Marly M

Primary Institution: Heart Institute (InCor-FMUSP) - São Paulo University, São Paulo, Brazil

Hypothesis

CMR may become an important method to stratify patients with Chagas' disease based on myocardial fibrosis.

Conclusion

CMR is an important technique for evaluating patients with Chagas' disease, highlighting significant morphological and functional differences.

Supporting Evidence

  • There is an inverse correlation between increasing Rassi’s score numbers and LV ejection fraction.
  • There is a strong correlation with the extent of myocardial fibrosis and the Rassi’s score.
  • Significant differences were observed in morphological and functional analysis between the two patient groups.

Takeaway

Doctors can use a special heart scan called CMR to see how sick someone is from Chagas' disease and help figure out who is at risk of getting worse.

Methodology

Patients underwent CMR examination to evaluate morphological and functional characteristics and the extent of myocardial fibrosis.

Participant Demographics

39 seropositive patients for Chagas' disease, divided into two groups based on cardiac involvement.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P293

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